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PHYLIP

PHYLIP is a set of modular programs for performing numerous types of phylogenetic analysis. Individual programs are broadly grouped into several categories: molecular sequence methods; distance matrix methods; analyses of gene frequencies and continuous characters; discrete characters methods; and tree drawing, consensus, tree editing, tree distances. Together the programs accommodate a broad range of data types including, DNA, RNA, protein, restriction sites, and general data types. The programs encompass a broad variety of analysis types including parsimony, compatibility, distance, invariants and maximum likelihood, and also include both jackknife and bootstrap re-sampling methods. The output from one program often forms the input for other programs within the package (e.g., dnadist generates a distance matrix from a file of DNA sequences, which is then used as input for neighbor to generate a neighbor-joining tree and the tree is then viewed with drawtree). Therefore for a typical analysis the user makes choices regarding each aspect of an analysis and chooses specific programs accordingly. Programs are run interactively via a text-based interface that provides a list of choices and prompts users for input.

Prerelease version 3.68

Input data file format

PHYLIP

Instructions

A demonstration of PHYLIP will be given by Joe Felsenstein.

Local documentation is available. There is also extensive documentation available on the web. Information on DNA Substitution Models is available locally. To learn more about the PHYLIP package go to the PHYLIP home page.

Jarno Tuimala's manual for the use of PHYLIP on molecular sequence data may also be helpful.

Sample files for the demonstration:
cytb.prt Cytochrome B protein sequences
eftualpha.prt EFTU Alpha protein sequences
fifteen.dna Large subunit rRNA sequences for 15 eukaryotes
fifteen.dst A set of distances for the above
hasegawa.dna Mitochondrial D-loop and adjacent 3rd positions for apes
primates.dna The same, for a wider range of primates
mamhbb.prt Mammalian hemoglobin beta sequences
mamhbb.dna Mammalian hemoglobin beta DNA sequences
mammalspenny.prt David Penny’s concatenation of mammal proteins
sarich.dst Immunological distances from Sarich 1969 Syst. Zool.
ten.prt COX II protein sequences of mammals
turbeville.dna Turbeville et al MBE 1994 large subunit rRNA for chordates
turbeville.wts 0/1 weights for the above identifying well-aligned regions

The font files (e.g., font1, font2, ...) are present in each user's home directory. These files are needed for drawgram and drawtree.

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Maintained by Adam Bazinet
Direct questions and comments to Michael Cummings